Digital droplet PCR (ddPCR) for the precise quantification of human T-lymphotropic virus 1 proviral loads in peripheral blood and cerebrospinal fluid of HAM/TSP patients and identification of viral mutations

An elevated human T cell lymphotropic virus 1 (HTLV)-1 proviral load (PVL) is the main risk factor for developing HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-1 infected subjects, and a high cerebrospinal fluid (CSF) to peripheral blood mononuclear cell (PBMC) PVL rati...

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Main Authors: Brunetto, Giovanna S., Massoud, Raya, Leibovitch, Emily C., Caruso, Breanna, Johnson, Kory, Ohayon, Joan, Fenton, Kaylan, Cortese, Irene, Jacobson, Steven
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085507/
https://ncbi.nlm.nih.gov/pubmed/24781526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-014-0249-3
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