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Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler’s virus–infected mice

The mechanisms underlying the initiation of virus-induced autoimmune disease are not well understood. Theiler’s murine encephalomyelitis virus–induced demyelinating disease (TMEV-IDD), a mouse model of multiple sclerosis, is initiated by TMEV-specific CD4(+) T cells targeting virally infected centra...

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Detalhes bibliográficos
Main Authors: Katz-Levy, Yael, Neville, Katherine L., Girvin, Ann M., Vanderlugt, Carol L., Pope, Jonathan G., Tan, Lit Jen, Miller, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC408545/
https://ncbi.nlm.nih.gov/pubmed/10487774
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