Urinary PGE-M levels are associated with risk of colorectal adenomas and chemopreventive response to anti-inflammatory drugs

Prostaglandin E(2) (PGE(2)) promotes colorectal carcinogenesis. Overall systemic PGE(2) production can be assessed by measuring its major metabolite, PGE-M, in urine. We examined the potential role of PGE-M as a biomarker for colorectal adenoma risk and chemopreventive response to anti-inflammatory...

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Main Authors: Bezawada, Navya, Song, Mingyang, Wu, Kana, Mehta, Raaj S., Milne, Ginger L., Ogino, Shuji, Fuchs, Charles S., Giovannucci, Edward L., Chan, Andrew T.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085181/
https://ncbi.nlm.nih.gov/pubmed/24824037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0120
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