GWAS and admixture mapping identify different asthma-associated loci in Latinos: The GALA II Study

BACKGROUND: Asthma is a complex disease with both genetic and environmental causes. Genome-wide association studies of asthma have mostly involved European populations and replication of positive associations has been inconsistent. OBJECTIVE: To identify asthma-associated genes in a large Latino pop...

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Main Authors: Galanter, Joshua M, Gignoux, Christopher R, Torgerson, Dara G, Roth, Lindsey A, Eng, Celeste, Oh, Sam S, Nguyen, Elizabeth A, Drake, Katherine A, Huntsman, Scott, Hu, Donglei, Sen, Saunak, Davis, Adam, Farber, Harold J., Avila, Pedro C., Brigino-Buenaventura, Emerita, LeNoir, Michael A., Meade, Kelley, Serebrisky, Denise, Borrell, Luisa N, Rodríguez-Cintrón, William, Estrada, Andres Moreno, Mendoza, Karla Sandoval, Winkler, Cheryl A., Klitz, William, Romieu, Isabelle, London, Stephanie J., Gilliland, Frank, Martinez, Fernando, Bustamante, Carlos, Williams, L Keoki, Kumar, Rajesh, Rodríguez-Santana, José R., Burchard, and Esteban G.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085159/
https://ncbi.nlm.nih.gov/pubmed/24406073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.08.055
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