Potential Role for HIV-Specific CD38(−)/HLA-DR(+) CD8(+) T Cells in Viral Suppression and Cytotoxicity in HIV Controllers

BACKGROUND: HIV controllers (HIC) are rare HIV-1-infected patients who exhibit spontaneous viral control. HIC have high frequency of CD38(−)/HLA-DR(+) HIV-specific CD8(+) T cells. Here we examined the role of this subset in HIC status. MATERIALS AND METHODS: We compared CD38(−)/HLA-DR(+) CD8(+) T ce...

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Détails bibliographiques
Auteurs principaux: Hua, Stéphane, Lécuroux, Camille, Sáez-Cirión, Asier, Pancino, Gianfranco, Girault, Isabelle, Versmisse, Pierre, Boufassa, Faroudy, Taulera, Olivier, Sinet, Martine, Lambotte, Olivier, Venet, Alain
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084978/
https://ncbi.nlm.nih.gov/pubmed/25000587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101920
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