Ancestry Estimation and Control of Population Stratification for Sequence-based Association Studies

Knowledge of individual ancestry is important for genetic association studies where population structure leads to false positive signals. Estimating individual ancestry with targeted sequence data, which constitutes the bulk of current sequence datasets, is challenging. Here, we propose a new method...

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Detalhes bibliográficos
Main Authors: Wang, Chaolong, Zhan, Xiaowei, Bragg-Gresham, Jennifer, Kang, Hyun Min, Stambolian, Dwight, Chew, Emily Y., Branham, Kari E., Heckenlively, John, Fulton, Robert, Wilson, Richard K., Mardis, Elaine R., Lin, Xihong, Swaroop, Anand, Zöllner, Sebastian, Abecasis, Gonçalo R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084909/
https://ncbi.nlm.nih.gov/pubmed/24633160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2924
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