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In Vitro Palmitate Treatment of Myotubes from Postmenopausal Women Leads to Ceramide Accumulation, Inflammation and Affected Insulin Signaling

Menopause is associated with an increased incidence of insulin resistance and metabolic diseases. In a chronic palmitate treatment model, we investigated the role of skeletal muscle fatty acid exposure in relation to the metabolic deterioration observed with menopause. Human skeletal muscle satellit...

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Detalhes bibliográficos
Main Authors: Abildgaard, Julie, Henstridge, Darren C., Pedersen, Anette T., Langley, Katherine G., Scheele, Camilla, Pedersen, Bente Klarlund, Lindegaard, Birgitte
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084812/
https://ncbi.nlm.nih.gov/pubmed/25000528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101555
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