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A computational framework for identifying design guidelines to increase the penetration of targeted nanoparticles into tumors

Targeted nanoparticles are increasingly being engineered for the treatment of cancer. By design, they can passively accumulate in tumors, selectively bind to targets in their environment, and deliver localized treatments. However, the penetration of targeted nanoparticles deep into tissue can be hin...

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Detalhes bibliográficos
Main Authors: Hauert, Sabine, Berman, Spring, Nagpal, Radhika, Bhatia, Sangeeta N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084751/
https://ncbi.nlm.nih.gov/pubmed/25009578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nantod.2013.11.001
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