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Evaluation of strain-induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions
OBJECTIVE: The purpose of this study was to investigate the effect of mechanical shear on hydrophobicity of pharmaceutical powder blends as a function of composition and particle size, and to determine the impact on drug release from tablets. METHODS: Four powder formulations were subjected to three...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4084706/ https://ncbi.nlm.nih.gov/pubmed/20942612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03639045.2010.521160 |
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