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High-Dose Methotrexate for the Treatment of Relapsed Central Nervous System Erdheim-Chester Disease
Erdheim-Chester disease (ECD) is a rare multisystem non-Langerhans histiocytosis. CNS involvement is a major complication, which is often rapidly progressive and confers a poor prognosis. However, treatment of CNS ECD is difficult due to poor CNS penetrance by the most effective chemotherapeutic dru...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4084618/ https://ncbi.nlm.nih.gov/pubmed/25031876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/269359 |
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