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B-Cell Mediated Pathogenesis of ANCA-Mediated Vasculitis

B cells and their progeny that produce and release anti-neutrophil cytoplasmic autoantibodies (ANCA) are the primary cause for an aggressive form of necrotizing small vessel vasculitis. Cytoplasmic ANCA antigens are released at the surface and in the microenvironment of cytokine-primed neutrophils....

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Detalhes bibliográficos
Main Authors: Jennette, J. Charles, Falk, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084547/
https://ncbi.nlm.nih.gov/pubmed/24777746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-014-0431-y
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