Fibroblast growth factor-2 mediates pressure-induced hypertrophic response

In vitro, fibroblast growth factor-2 (FGF2) has been implicated in cardiomyocyte growth and reexpression of fetal contractile genes, both markers of hypertrophy. However, its in vivo role in cardiac hypertrophy during pressure overload is not well characterized. Mice with or without FGF2 (Fgf2(+/+)...

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Publicat a:J Clin Invest
Autors principals: Schultz, Jo El J., Witt, Sandra A., Nieman, Michelle L., Reiser, Peter J., Engle, Sandra J., Zhou, Ming, Pawlowski, Sharon A., Lorenz, John N., Kimball, Thomas R., Doetschman, Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1999
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408439/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10491406/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7315
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