IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation

We recently showed that IL-11 prevents lethal graft-versus-host disease (GVHD) in a murine bone marrow transplantation (BMT) model of GVHD directed against MHC and minor antigens. In this study, we have investigated whether IL-11 can maintain a graft-versus-leukemia (GVL) effect. Lethally irradiated...

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Autors principals: Teshima, Takanori, Hill, Geoffrey R., Pan, Luying, Brinson, Yani S., van den Brink, Marcel R.M., Cooke, Kenneth R., Ferrara, James L.M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1999
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC408425/
https://ncbi.nlm.nih.gov/pubmed/10430613
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