Major peptide autoepitopes for nucleosome-specific T cells of human lupus

We tested 154 peptides spanning the entire length of core histones of nucleosomes for the ability to stimulate an anti-DNA autoantibody–inducing T helper (Th) clone, as well as CD4(+) T-cell lines and T cells, in fresh PBMCs from 23 patients with lupus erythematosus. In contrast to normal T cells, l...

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Main Authors: Lu, Liangjun, Kaliyaperumal, Arunan, Boumpas, Dimitrios T., Datta, Syamal K.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC408421/
https://ncbi.nlm.nih.gov/pubmed/10430616
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