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Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5.

Gene targeting was used to create mice with a null mutation of the gene encoding the common beta subunit (beta C) of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin 3 (IL-3; multi-CSF), and interleukin 5 (IL-5) receptor complexes (beta C-/- mice). High-affinity binding of...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Robb, L, Drinkwater, C C, Metcalf, D, Li, R, Köntgen, F, Nicola, N A, Begley, C G
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40842/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568173/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.21.9565
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