Chronic Neuroinflammation in Alzheimer's Disease: New Perspectives on Animal Models and Promising Candidate Drugs

Chronic neuroinflammation is now considered one of the major factors in the pathogenesis of Alzheimer's disease (AD). However, the most widely used transgenic AD models (overexpressing mutated forms of amyloid precursor protein, presenilin, and/or tau) do not demonstrate the degree of inflammat...

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Hlavní autoři: Millington, Christopher, Sonego, Sandra, Karunaweera, Niloo, Rangel, Alejandra, Aldrich-Wright, Janice R., Campbell, Iain L., Gyengesi, Erika, Münch, Gerald
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
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Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083880/
https://ncbi.nlm.nih.gov/pubmed/25025046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/309129
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