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Glial Cell Line-derived Neurotrophic Factor Regulation of Genes Essential for Self-renewal of Mouse Spermatogonial Stem Cells Is Dependent on Src Family Kinase Signaling

Self-renewal and differentiation by spermatogonial stem cells (SSCs) is the foundation for continual spermatogenesis. SSC self-renewal is dependent on glial cell line-derived neurotrophic factor (GDNF); however, intracellular mechanisms stimulated by GDNF in SSCs are unknown. To investigate these me...

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Detalhes bibliográficos
Main Authors: Oatley, Jon M., Avarbock, Mary R., Brinster, Ralph L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083858/
https://ncbi.nlm.nih.gov/pubmed/17597063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703474200
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