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Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies

Sle1 and Sle3 are 2 loci that confer susceptibility to lupus nephritis in the NZM2410 strain of mice. Our previous work has shown that B6.NZMc1 mice, congenic for Sle1, exhibit loss of tolerance to chromatin but do not develop any pathogenic autoantibodies or disease. B6.NZMc7 mice, congenic for Sle...

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Main Authors: Mohan, Chandra, Morel, Laurence, Yang, Ping, Watanabe, Hiroshi, Croker, Byron, Gilkeson, Gary, Wakeland, Edward K.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC408382/
https://ncbi.nlm.nih.gov/pubmed/10377175
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