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Examination of VLC-PUFA–Deficient Photoreceptor Terminals

PURPOSE. Juvenile-onset autosomal dominant Stargardt-like macular dystrophy (STGD3) is caused by mutations in ELOVL4 (elongation of very long fatty acids-4), an elongase necessary for the biosynthesis of very long chain fatty acids (VLC-FAs ≥ C26). Photoreceptors are enriched with VLC polyunsaturate...

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Detalhes bibliográficos
Main Authors: Bennett, Lea D., Hopiavuori, Blake R., Brush, Richard S., Chan, Michael, Van Hook, Matthew J., Thoreson, Wallace B., Anderson, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083770/
https://ncbi.nlm.nih.gov/pubmed/24764063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-13997
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