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Regulation of Mitochondrial Genome Inheritance by Autophagy and Ubiquitin-Proteasome System: Implications for Health, Fitness, and Fertility

Mitochondria, the energy-generating organelles, play a role in numerous cellular functions including adenosine triphosphate (ATP) production, cellular homeostasis, and apoptosis. Maternal inheritance of mitochondria and mitochondrial DNA (mtDNA) is universally observed in humans and most animals. In...

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Bibliographic Details
Main Authors: Song, Won-Hee, Ballard, John William Oman, Yi, Young-Joo, Sutovsky, Peter
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083708/
https://ncbi.nlm.nih.gov/pubmed/25028670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/981867
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