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Role of leukotriene A(4) hydrolase aminopeptidase in the pathogenesis of emphysema()
The leukotriene A(4) hydrolase (LTA(4)H) is a bi-functional enzyme with an epoxy hydrolase and aminopeptidase activities. We hypothesize that the LTA(4)H aminopeptidase activity alleviates neutrophilic inflammation, which contributes to cigarette smoke (CS)-induced emphysema by clearing Proline-Glyc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4083682/ https://ncbi.nlm.nih.gov/pubmed/24771855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400452 |
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