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Role of leukotriene A(4) hydrolase aminopeptidase in the pathogenesis of emphysema()

The leukotriene A(4) hydrolase (LTA(4)H) is a bi-functional enzyme with an epoxy hydrolase and aminopeptidase activities. We hypothesize that the LTA(4)H aminopeptidase activity alleviates neutrophilic inflammation, which contributes to cigarette smoke (CS)-induced emphysema by clearing Proline-Glyc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Paige, Mikell, Wang, Kan, Burdick, Marie, Park, Sunhye, Cha, Josiah, Jeffrey, Erin, Sherman, Nicholas, Shim, Y. Michael
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083682/
https://ncbi.nlm.nih.gov/pubmed/24771855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400452
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