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Conformational B-Cell Epitopes Prediction from Sequences Using Cost-Sensitive Ensemble Classifiers and Spatial Clustering

B-cell epitopes are regions of the antigen surface which can be recognized by certain antibodies and elicit the immune response. Identification of epitopes for a given antigen chain finds vital applications in vaccine and drug research. Experimental prediction of B-cell epitopes is time-consuming an...

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Autori principali: Zhang, Jian, Zhao, Xiaowei, Sun, Pingping, Gao, Bo, Ma, Zhiqiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083607/
https://ncbi.nlm.nih.gov/pubmed/25045691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/689219
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