IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

IL-17 is a newly discovered T cell–derived cytokine whose role in osteoclast development has not been fully elucidated. Treatment of cocultures of mouse hemopoietic cells and primary osteoblasts with recombinant human IL-17 induced the formation of multinucleated cells, which satisfied major criteri...

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Autori principali: Kotake, Shigeru, Udagawa, Nobuyuki, Takahashi, Naoyuki, Matsuzaki, Kenichiro, Itoh, Kanami, Ishiyama, Shigeru, Saito, Seiji, Inoue, Kazuhiko, Kamatani, Naoyuki, Gillespie, Matthew T., Martin, T. John, Suda, Tatsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC408356/
https://ncbi.nlm.nih.gov/pubmed/10225978
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