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Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros

Development of the embryonic kidney results from reciprocal signaling between the ureteric bud and the metanephric mesenchyme. To identify the signaling molecules, we developed an assay in which metanephric mesenchymes are rescued from apoptosis by factors secreted from ureteric bud cells (UB cells)...

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Detalhes bibliográficos
Main Authors: Barasch, Jonathan, Yang, Jun, Qiao, Jizeng, Tempst, Paul, Erdjument-Bromage, Hediye, Leung, Winnie, Oliver, Juan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC408351/
https://ncbi.nlm.nih.gov/pubmed/10225973
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