Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions

PURPOSE: Cancer immunotherapy with adoptive transfer of tumor infiltrating lymphocytes (TILs) represents an effective treatment for patients with metastatic melanoma, with the objective regressions in up to 72% of patients in three clinical trials. However, the antigen targets recognized by these ef...

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Autori principali: Lu, Yong-Chen, Yao, Xin, Crystal, Jessica S., Li, Yong F., El-Gamil, Mona, Gross, Colin, Davis, Lindy, Dudley, Mark E., Yang, James C., Samuels, Yardena, Rosenberg, Steven A., Robbins, Paul F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083471/
https://ncbi.nlm.nih.gov/pubmed/24987109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0433
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