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Asymmetric Insertion of Membrane Proteins in Lipid Bilayers by Solid-State NMR Paramagnetic Relaxation Enhancement: A Cell-Penetrating Peptide Example

A novel solid-state NMR technique for identifying the asymmetric insertion depths of membrane proteins in lipid bilayers is introduced. By applying Mn(2+) ions on the outer but not the inner leaflet of lipid bilayers, the sidedness of protein residues in the lipid bilayer can be determined through p...

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Hlavní autoři: Su, Yongchao, Mani, Rajeswari, Hong, Mei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083468/
https://ncbi.nlm.nih.gov/pubmed/18597439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja802383t
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