Developmental programming by high fructose decreases phosphorylation efficiency in aging offspring brain mitochondria, correlating with enhanced UCP5 expression

Fructose has recently been observed to affect brain metabolism and cognitive function in adults. Yet, possible late-onset effects by gestational fructose exposure have not been examined. We evaluated mitochondrial function in the brain of aging (15 months) male offspring of Fischer F344 rat dams fed...

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Detalhes bibliográficos
Main Authors: Mortensen, Ole H, Larsen, Lea H, Ørstrup, Laura KH, Hansen, Lillian HL, Grunnet, Niels, Quistorff, Bjørn
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083386/
https://ncbi.nlm.nih.gov/pubmed/24756078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.72
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