Aged Human Mesenchymal Stem Cells: The Duration of Bone Morphogenetic Protein-2 Stimulation Determines Induction or Inhibition of Osteogenic Differentiation

Bone morphogenetic protein 2 (BMP-2) is a potent osteoinductive cytokine and a growing number of in vitro studies analyze its effects on human mesenchymal stem cells (hMSC) derived from aged or osteoporotic donors. In these studies the exact quantification of osteogenic differentiation capacity is o...

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Detalhes bibliográficos
Main Authors: Heggebö, Jostein, Haasters, Florian, Polzer, Hans, Schwarz, Christina, Saller, Maximilian Michael, Mutschler, Wolf, Schieker, Matthias, Prall, Wolf Christian
Formato: Artigo
Idioma:Inglês
Publicado em: PAGEPress Publications, Pavia, Italy 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083304/
https://ncbi.nlm.nih.gov/pubmed/25002931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/or.2014.5242
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