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Pathogenesis of Chronic Hyperglycemia: From Reductive Stress to Oxidative Stress

Chronic overnutrition creates chronic hyperglycemia that can gradually induce insulin resistance and insulin secretion impairment. These disorders, if not intervened, will eventually be followed by appearance of frank diabetes. The mechanisms of this chronic pathogenic process are complex but have b...

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Detalhes bibliográficos
Autor principal: Yan, Liang-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082845/
https://ncbi.nlm.nih.gov/pubmed/25019091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/137919
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