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Overexpression of glycine-extended gastrin in transgenic mice results in increased colonic proliferation

Gastrin is a peptide hormone involved in the growth of both normal and malignant gastrointestinal tissue. Recent studies suggest that the glycine-extended biosynthetic intermediates mediate many of these trophic effects, but the in vivo relevance of glycine-extended gastrin (G-Gly) has not been test...

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Main Authors: Koh, Theodore J., Dockray, Graham J., Varro, Andrea, Cahill, Rachel J., Dangler, Charles A., Fox, James G., Wang, Timothy C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC408271/
https://ncbi.nlm.nih.gov/pubmed/10207163
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