Colitis and Colon Cancer in WASP-Deficient Mice Require Helicobacter Spp.

BACKGROUND: Wiskott-Aldrich Syndrome protein (WASP)-deficient patients and mice are immunodeficient and can develop inflammatory bowel disease. The intestinal microbiome is critical to the development of colitis in most animal models, in which, Helicobacter spp. have been implicated in disease patho...

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Hoofdauteurs: Nguyen, Deanna D., Muthupalani, Suresh, Goettel, Jeremy A., Eston, Michelle A., Mobley, Melissa, Taylor, Nancy S., McCabe, Amanda, Marin, Romela, Snapper, Scott B., Fox, James G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082694/
https://ncbi.nlm.nih.gov/pubmed/23820270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e318295fd8f
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