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Proteolysis of monocyte CD14 by human leukocyte elastase inhibits lipopolysaccharide-mediated cell activation

Human leukocyte elastase (HLE), a polymorphonuclear neutrophil (PMN) serine proteinase, is proteolytically active on some membrane receptors at the surface of immune cells. The present study focused on the effect of HLE on the expression of CD14, the main bacterial lipopolysaccharide (LPS) receptor...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Le-Barillec, Karine, Si-Tahar, Mustapha, Balloy, Viviane, Chignard, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408261/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10194477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5779
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