Proteolysis of monocyte CD14 by human leukocyte elastase inhibits lipopolysaccharide-mediated cell activation

Human leukocyte elastase (HLE), a polymorphonuclear neutrophil (PMN) serine proteinase, is proteolytically active on some membrane receptors at the surface of immune cells. The present study focused on the effect of HLE on the expression of CD14, the main bacterial lipopolysaccharide (LPS) receptor...

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Main Authors: Le-Barillec, Karine, Si-Tahar, Mustapha, Balloy, Viviane, Chignard, Michel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1999
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC408261/
https://ncbi.nlm.nih.gov/pubmed/10194477
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