The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery

BACKGROUND: The bitter taste receptor T2R38 was recently described to play a role in upper airway innate mucosal defense. When activated by bacterial quorum-sensing molecules, T2R38 stimulates the ciliated epithelial cells to produce nitric oxide (NO), resulting in bactericidal activity and an incre...

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Bibliographische Detailangaben
Hauptverfasser: Adappa, Nithin D., Zhang, Zi, Palmer, James N., Kennedy, David W., Doghramji, Laurel, Lysenko, Anna, Reed, Danielle R., Scott, Thomas, Zhao, Nina W., Owens, David, Lee, Robert J., Cohen, Noam A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082560/
https://ncbi.nlm.nih.gov/pubmed/24302675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.21253
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