Immunotherapy Converts Non-immunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation

Pancreatic ductal adenocarcinoma (PDAC) is considered a “non-Immunogenic” neoplasm. Single agent immunotherapies have failed to demonstrate significant clinical activity in PDAC and other “non-immunogenic” tumors, in part due to a complex tumor microenvironment (TME) that provides a formidable barri...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lutz, Eric R., Wu, Annie A., Bigelow, Elaine, Sharma, Rajni, Mo, Guanglan, Soares, Kevin, Solt, Sara, Dorman, Alvin, Wamwea, Anthony, Yager, Allison, Laheru, Daniel, Wolfgang, Christopher L., Wang, Jiang, Hruban, Ralph H., Anders, Robert A., Jaffee, Elizabeth M., Zheng, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082460/
https://ncbi.nlm.nih.gov/pubmed/24942756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0027
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados