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Impact of Farnesylation Inhibitors on Survival in Hutchinson-Gilford Progeria Syndrome

BACKGROUND: Hutchinson-Gilford progeria syndrome is an ultra-rare segmental premature aging disease resulting in early death from heart attack or stroke. There is no approved treatment, but starting in 2007, several recent single arm clinical trials have administered inhibitors of protein farnesylat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gordon, Leslie B., Massaro, Joe, D'Agostino, Ralph B., Campbell, Susan E., Brazier, Joan, Brown, W. Ted, Kleinman, Monica E, Kieran, Mark W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082404/
https://ncbi.nlm.nih.gov/pubmed/24795390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.008285
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