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Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin
Dalbavancin, a semi-synthetic glycopeptide with enhanced antibiotic activity compared to vancomycin and teicoplanin, binds to the C-terminal lysyl-d-alanyl-d-alanine subunit of Lipid II, inhibiting peptidoglycan biosynthesis. In this study, micro-calorimetry and electrospray ionization (ESI)-MS have...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Royal Society of Chemistry
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4082399/ https://ncbi.nlm.nih.gov/pubmed/24608916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob42428f |
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