Insights into the Human Glycan Receptor Conformation of 1918 Pandemic Hemagglutinin–Glycan Complexes Derived from Nuclear Magnetic Resonance and Molecular Dynamics Studies

[Image: see text] The glycan receptor binding and specificity of influenza A viral hemagglutinin (HA) are critical for virus infection and transmission in humans. However, ambiguities in the interpretation of the receptor binding specificity of hemagglutinin from human- and avian-adapted viruses hav...

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Detalhes bibliográficos
Main Authors: Elli, Stefano, Macchi, Eleonora, Rudd, Timothy R., Raman, Rahul, Sassaki, Guillherme, Viswanathan, Karthik, Yates, Edwin A., Shriver, Zachary, Naggi, Annamaria, Torri, Giangiacomo, Sasisekharan, Ram, Guerrini, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082378/
https://ncbi.nlm.nih.gov/pubmed/24878075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500338r
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