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Eccentric muscle challenge shows osteopontin polymorphism modulation of muscle damage

A promoter polymorphism of the osteopontin (OPN) gene (rs28357094) has been associated with multiple inflammatory states, severity of Duchenne muscular dystrophy (DMD) and muscle size in healthy young adults. We sought to define the mechanism of action of the polymorphism, using allele-specific in v...

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Autors principals: Barfield, Whitney L., Uaesoontrachoon, Kitipong, Wu, Chung-Sheih, Lin, Stephen, Chen, Yue, Wang, Paul C., Kanaan, Yasmine, Bond, Vernon, Hoffman, Eric P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082368/
https://ncbi.nlm.nih.gov/pubmed/24626632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu118
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