Increased density of inhibitory noradrenergic parenchymal nerve fibers in hypertrophic islets of Langerhans of obese mice

BACKGROUND AND AIM: We sought to identify mechanisms of beta cell failure in genetically obese mice. Little is known about the role of pancreatic innervation in the progression of beta cell failure. In this work we studied adrenergic innervation, in view of its potent inhibitory effect on insulin se...

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Hauptverfasser: Giannulis, I., Mondini, E., Cinti, F., Frontini, A., Murano, I., Barazzoni, R., Barbatelli, G., Accili, D., Cinti, S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082304/
https://ncbi.nlm.nih.gov/pubmed/24462047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.numecd.2013.09.006
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