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A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense.

In this paper we report a recessive mutation, immune deficiency (imd), that impairs the inducibility of all genes encoding antibacterial peptides during the immune response of Drosophila. When challenged with bacteria, flies carrying this mutation show a lower survival rate than wild-type flies. We...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lemaitre, B, Kromer-Metzger, E, Michaut, L, Nicolas, E, Meister, M, Georgel, P, Reichhart, J M, Hoffmann, J A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568155/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.21.9465
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