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Structural-Functional Analysis of the Third Transmembrane Domain of the Corticotropin-releasing Factor Type 1 Receptor: ROLE IN ACTIVATION AND ALLOSTERIC ANTAGONISM
The corticotropin-releasing factor (CRF) type 1 receptor (CRF(1)R) for the 41-amino acid peptide CRF is a class B G protein-coupled receptor, which plays a key role in the response of our body to stressful stimuli and the maintenance of homeostasis by regulating neural and endocrine functions. CRF a...
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| Huvudupphovsmän: | , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081936/ https://ncbi.nlm.nih.gov/pubmed/24838244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544460 |
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