Innate Immune Responses and Rapid Control of Inflammation in African Green Monkeys Treated or Not with Interferon-Alpha during Primary SIVagm Infection

Chronic immune activation (IA) is considered as the driving force of CD4(+) T cell depletion and AIDS. Fundamental clues in the mechanisms that regulate IA could lie in natural hosts of SIV, such as African green monkeys (AGMs). Here we investigated the role of innate immune cells and IFN-α in the c...

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Main Authors: Jacquelin, Béatrice, Petitjean, Gaël, Kunkel, Désirée, Liovat, Anne-Sophie, Jochems, Simon P., Rogers, Kenneth A., Ploquin, Mickaël J., Madec, Yoann, Barré-Sinoussi, Françoise, Dereuddre-Bosquet, Nathalie, Lebon, Pierre, Le Grand, Roger, Villinger, François, Müller-Trutwin, Michaela
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081777/
https://ncbi.nlm.nih.gov/pubmed/24991927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004241
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