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Exome Sequencing from Nanogram Amounts of Starting DNA: Comparing Three Approaches
Hybridization-based target enrichment protocols require relatively large starting amounts of genomic DNA, which is not always available. Here, we tested three approaches to pre-capture library preparation starting from 10 ng of genomic DNA: (i and ii) whole-genome amplification of DNA samples with R...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081514/ https://ncbi.nlm.nih.gov/pubmed/24992588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101154 |
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