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Methanandamide attenuates cocaine-induced hyperthermia in rats by a cannabinoid CB(1)-dopamine D(2) receptor mechanism

Evidence implicates anandamide in dopamine-related cocaine function. In the present study, we investigated the effect of methanandamide (5 mg/kg, i.p.), a stable anandamide analog, on the hyperthermia and hyperactivity induced by a fixed dose of cocaine (15 mg/kg, i.p.). Cocaine administered to rats...

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Main Authors: Rasmussen, Bruce A., Kim, Esther, Unterwald, Ellen M., Rawls, Scott M.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081499/
https://ncbi.nlm.nih.gov/pubmed/19401177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.12.078
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