Inhibition of allorecognition by a human class II MHC–derived peptide through the induction of apoptosis

The interaction of the T-cell receptor with the major histocomatibility complex (MHC)–peptide complex is central to T-cell activation. Variation in the nature of the peptide bound within the groove of the MHC molecule may result in an altered T-cell response. Because some naturally processed peptide...

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Hauptverfasser: Murphy, Barbara, Magee, Colm C., Alexander, Stephen I., Waaga, Ana Maria, Snoeck, Hans W., Vella, John P., Carpenter, Charles B., Sayegh, Mohamed H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC408148/
https://ncbi.nlm.nih.gov/pubmed/10079107
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