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MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B

The earliest recognizable atherosclerotic lesions are fatty streaks composed of lipid-laden macrophages (foam cells). Circulating monocytes are the precursors of these foam cells, but the molecular mechanisms that govern macrophage trafficking through the vessel wall are poorly understood. Monocyte...

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Autori principali: Gosling, Jennifa, Slaymaker, Sarah, Gu, Long, Tseng, Susan, Zlot, Constance H., Young, Stephen G., Rollins, Barrett J., Charo, Israel F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC408147/
https://ncbi.nlm.nih.gov/pubmed/10079097
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