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Tranilast Increases Vasodilator Response to Acetylcholine in Rat Mesenteric Resistance Arteries through Increased EDHF Participation

BACKGROUND AND PURPOSE: Tranilast, in addition to its capacity to inhibit mast cell degranulation, has other biological effects, including inhibition of reactive oxygen species, cytokines, leukotrienes and prostaglandin release. In the current study, we analyzed whether tranilast could alter endothe...

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Bibliografiska uppgifter
Huvudupphovsmän: Xavier, Fabiano E., Blanco-Rivero, Javier, Sastre, Esther, Caracuel, Laura, Callejo, María, Balfagón, Gloria
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081117/
https://ncbi.nlm.nih.gov/pubmed/24992476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100356
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