Structural and functional implications of the QUA2 domain on RNA recognition by GLD-1

The STAR family comprises ribonucleic acid (RNA)-binding proteins that play key roles in RNA-regulatory processes. RNA recognition is achieved by a KH domain with an additional α-helix (QUA2) that seems to extend the RNA-binding surface to six nucleotides for SF1 (Homo sapiens) and seven nucleotides...

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Detalles Bibliográficos
Autores principales: Daubner, Gerrit M., Brümmer, Anneke, Tocchini, Cristina, Gerhardy, Stefan, Ciosk, Rafal, Zavolan, Mihaela, Allain, Frédéric H.-T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081071/
https://ncbi.nlm.nih.gov/pubmed/24838563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku445
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