Multiple-Integrations of HPV16 Genome and Altered Transcription of Viral Oncogenes and Cellular Genes Are Associated with the Development of Cervical Cancer

The constitutive expression of the high-risk HPV E6 and E7 viral oncogenes is the major cause of cervical cancer. To comprehensively explore the composition of HPV16 early transcripts and their genomic annotation, cervical squamous epithelial tissues from 40 HPV16-infected patients were collected fo...

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Bibliografiske detaljer
Main Authors:	Lu, Xulian, Lin, Qiaoai, Lin, Mao, Duan, Ping, Ye, Lulu, Chen, Jun, Chen, Xiangmin, Zhang, Lifang, Xue, Xiangyang
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science 2014
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4081011/ https://ncbi.nlm.nih.gov/pubmed/24992025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097588
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Multiple-Integrations of HPV16 Genome and Altered Transcription of Viral Oncogenes and Cellular Genes Are Associated with the Development of Cervical Cancer

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