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Surfactant protein A suppresses reactive nitrogen intermediates by alveolar macrophages in response to Mycobacterium tuberculosis

Mycobacterium tuberculosis attaches to, enters, and replicates within alveolar macrophages (AMs). Our previous studies suggest that surfactant protein A (SP-A) can act as a ligand in the attachment of M. tuberculosis to AMs. Reactive nitrogen intermediates (RNIs) play a significant role in the killi...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Pasula, Rajamouli, Wright, Jo Rae, Kachel, Diane L., Martin, William J.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408094/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10021456/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2991
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